Photo of School of Pharmacy NMR room

NMR at the UCL School of Pharmacy

The in-house NMR facility in the School of Pharmacy has recently been upgraded (Summer 2022) with a new 600 MHz spectrometer, and re-consoling of our 400 MHz instrument (used primarily for chemistry). In addition, we have a new liquid handling robot allowing rapid preparation of 96 tube racks of NMR samples, with applications for high throughput screening and metabolomics.

  • 600 MHz Avance NEO QCI-F cryoprobe (13C, 15N, 1H, 19F) with cooled SampleJet
  • 400 MHz Avance NEO nanobay BBFO iProbe (1H, 15N to 19F)
  • with 60-position Sample Case
  • SamplePro Tube liquid handling robot, for automated transfer from 96 well plates and racks of vials to 3 mm and 5 mm NMR tubes
Photo of Darwin building NMR room

NMR across UCL

Beyond the School of Pharmacy, UCL is extremely well-equipped for solution-state biomolecular NMR, with an extensive range of spectrometers and probes available within the Darwin building, assisted by an experienced facility manager, Angelo Figueirido:

  • 800 MHz TCI cryoprobe (1H, 15N, 13C, 2H)
  • 700 MHz TCI cryoprobe (1H, 15N, 13C, 2H)
  • 600 MHz TXO cryoprobe (13C, 15N, 1H, 2H, optimised for 13C detection)
  • 500 MHz TCI Prodigy cryoprobe (1H/19F, 15N, 13C, 2H) with SampleJet
Photo of 950 MHz spectrometer at Francis Crick Institute

National Facilities

We are just 5 min away from the Francis Crick Institute, which hosts the national MRC Biomedical NMR Centre. This provides routine access to a range of field strengths from 600 to 950 MHz, including solid-state HR-MAS capabilities.

We are also regular users of the national 1 GHz spectrometer hosted at HWB-NMR in Birmingham.